Verapamil is a calcium channel blocker, it treats high blood pressure relaxing and widening blood vessels.
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Common useArpamyl is a Ca2+-channel blocker which relaxes (widens) veins and arteries, which makes it easier for the heart to pump and this way Arpamyl reduces its workload. Calcium triggers contraction of smooth muscles and when its entrance to the myocytes, it results in relaxation of the arterial muscles, improved oxygen delivery to the myocardial tissue, and decreased total peripheral resistance, systemic blood pressure, and afterload. Arpamyl also decreases the conduction of electrical impulses through the heart that control the coordination of contraction, this slows the rate of contraction. Arpamyl is used to treat hypertension, to treat angina, control some types of irregular heartbeats.
Dosage and directionTake orally with or without food. Daily dose is 180-480 mg which may be taken as a single dose or divided in two or three intakes. Take exactly as prescribed by your doctor, never exceed the dose recommended to you.
PrecautionsAvoid drinking alcoholic beverages, grapefruit juice or eating grapefruit. Alcohol is able worsen side effects of Arpamyl (drowsiness and dizziness ) while grapefruit interacts with components of the drug. Do not get up too fast from a sitting or lying position as you may feel dizzy.
ContraindicationsArpamyl is contraindicated in patients with hypersensitivity to components of the medication, severe left ventricular dysfunction, hypotension (systolic pressure less than 90 mm Hg) or cardiogenic shock, sick sinus syndrome (except in patients with a functioning artificial ventricular pacemaker), atrioventricular block degree II-III (except in patients with a functioning artificial ventricular pacemaker), atrial flutter or atrial fibrillation and an accessory bypass tract (Wolff-Parkinson-White, Lown-Ganong-Levine syndromes). Side effects Arpamyl is usually well tolerated. Most common side effects include dizziness, weakness or fainting, swelling of the lower extremities, rash, headache, and constipation. Jaundice, swelling, difficulty breathing, rashes are also possible. If you experience severe side effects listed above seek for immediate medical attention.
Drug interactionArpamyl inhibits elimination of alcohol, increases the efficacy of doxorubicin both in tissue culture systems and in patients. Cyclophosphamide, oncovin, procarbazine, prednisone (COPP) and the vindesine, adriamycin, cisplatin (VAC) cytotoxic drug regimens are able to decrease absorption of Arpamyl. Co-administration of Arpamyl with aspiring in rare cases increases risk of bleeding. Correction of digoxin dosage is important in patients treated with Arpamyl. Chronic verapamil treatment can increase serum digoxin levels by 50% to 75% during the first week of therapy leading to digitalis toxicity. Co-administration with oral antihypertensive agents results in additive effects. Inform your doctor about all medications you take, especially about Disopyramide, Flecainide, Quinidine, Phenobarbital, Cyclosporin, medications which contain lithium. This medication may change results of certain liver tests to mildly abnormal.
Missed doseTake the dose you forgot as soon as you remember. If it is almost time for your next intake just skip the next dose and return to your regular schedule.
OverdoseIf you experience slow heartbeat and fainting, they may be symptoms of overdose. Seek for immediate medical attention if you suppose that too much of Arpamyl was taken.
StorageStore at room temperature 15-30 C (59-86 F) away from light, moisture, pets and children.
DisclaimerWe provide only general information about medications which does not cover all directions, possible drug integrations, or precautions. Information at the site cannot be used for self-treatment and self-diagnosis. Any specific instructions for a particular patient should be agreed with your health care adviser or doctor in charge of the case. We disclaim reliability of this information and mistakes it could contain. We are not responsible for any direct, indirect, special or other indirect damage as a result of any use of the information on this site and also for consequences of self-treatment.
Important Information about Purchasing VerapamilIn some countries valid doctor's prescription is required to purchase Verapamil. Our online pharmacy escrow service allows You to buy Verapamil without a prescription as its not required in the country where this medicine is purchased and shipped from (India). We expect that You are familiar with the Verapamil medication You want to buy online. You must know needed dosage that works for You, how to take this drug and all possible side effects.
We guarantee quality of Verapamil - arpamyl medication that is sold through our site. Its medical effect will be the same as of brand name Verapamil®.